Sam, Steven, and Tahoe have a new paper on the asymmetric di-pi-methane rearrangement up on JOC today. This one is an homage to Howard Zimmerman, the pioneering organic photochemist who discovered the reaction and studied …
News
Enantioselective strain-releasing [2π + 2σ] cycloadditions of BCBs
Ellie, Zoe, and Rodrigo report a Brønsted acid catalyzed asymmetric [2π + 2σ] cycloaddition in JACS, providing a straightforward route to rigid chiral bicycles in highly enantioenriched form. A terrific collaboration with GSK and Corteva …
TA Award for Katie
Congratulations to our teammate Katie, who received one of three Organic Outstanding TA Award from the Department! Undergraduate teaching in Chemistry is a huge communal effort: every semester, we hire ~180 talented chemists to lead …
Truxinate Org Syn Prep
Our star undergraduate Rodrigo wondered if a commercial chiral Brønsted acid could be used in our asymmetric photochemistry instead of the optimal BINOL-derived triflimide we originally used. The answer is yes! Rodrigo reports the enantioselective …
Understanding photocatalytic aziridination
Alana, Mihai, and Arindam formed an unstoppable collaboration team through the SuPRCat CCI with the Paton and Damrauer groups to understand a new, remarkably general method for photocatalytic alkene aziridination. A combination of preparative, computational, …
Predicting Ir emissions using AI
We had a great collaboration with the Schmidt group on an AI model for predicting the emission spectra of Ir complexes. Based on a big data set collected and published by the Bernhard group. Now …
Asymmetric Paternò–Büchi Reaction
Jesse, Tahoe, Wes, and Yerin have a terrific new paper in JACS today about the long road to an asymmetric catalytic Paternò–Büchi reaction. A great collaboration with Kent and the Wright lab at UW.
Solid-state synthesis of the truxillates
In JACS today, Ellie, Hyung Joo, and Matt report a general approach to the truillate family of natural products enabled by solid state photochemistry. Synthetically, this paper complements the route to the truxinates we published …
Enantioselective 6π Photoelectrocyclizations
The latest chapter in our ongoing collaboration with the Baik group is now published in JACS. Wes and Hanna lead a comprehensive synthetic, spectroscopic, and computational study of highly enantioselective 6π photoelectrocyclizations. Previously on the …
Cu oxidant review
A coda to Grace’s successful PhD career: her review describing the use of Cu(II) salts as terminal oxidants in photochemical reactions is online at OBMC.