Cooperative Photocatalytic Stereocontrol

In the process of developing an enantioselective [2+2] photocycloaddition of vinylpyridines, Steven and Wes discovered stereochemical cooperativity between a chiral Brønsted acid catalyst and a chiral Ir photocatalyst. It’s a gratifying demonstration that matched/mismatched effects …

Cu-mediated Decarboxylative Coupling

The Yoon lab’s first publication of 2022 is a new oxidative decarboxylative coupling process based on the intrinsic photochemistry of Cu(II) carboxylate complexes. Check out the paper in Nature Chemistry. Congratulations Yukki, Sam, Grace, Kimberly, …

Brønsted Acid Catalyzed Chromophore Activation

Evan, Matt, and Bohyun investigated a novel strategy for highly enantioselective organocatalytic photochemistry in which no individual reaction component absorbs light. Very pleased to announce the publication of this collaborative project with the Baik group …

Oxidative Alkene Functionalizations

Nic and Grace have developed a protocol for intramolecular oxidative functionalization of sterically bulky alkenes with diverse heteronucleophiles as a way to show that photoredox catalysis can address long-standing limitations of transition metal catalyzed processes. …

Divergent Photoreactions of Ketones

Jian and Xiao’s study of the divergent reactions of benzoylformates is online at Org Lett! This paper shows how the rational choice of reaction conditions can partition a photocatalytic reaction between photoredox and triplet sensitization …