Cu-mediated Decarboxylative Coupling

The Yoon lab’s first publication of 2022 is a new oxidative decarboxylative coupling process based on the intrinsic photochemistry of Cu(II) carboxylate complexes. Check out the paper in Nature Chemistry. Congratulations Yukki, Sam, Grace, Kimberly, and our great team of collaborators at Pfizer!

For a video walkthrough of how to set up this reaction, as well as some behind-the-scenes background on the origins of this method, take a look at Sam’s blog post.