Tahoe, Omar, and Jesse report a new approach to oxetane synthesis that turns the classical mechanism of the Paternò–Büchi reaction on its head. Proud of our contribution to the 15th anniversary Chem Sci collection.
Month: November 2025
Oxygen migration into C–C bonds
How do you functionalize a C–C bond? Cade, Caitlin, Matthieu, and Felix have a compelling method for migrating an oxygen atom into an unstrained C(sp3)–C(sp3) bond. In cyclic contexts, this enables the editing of a …
Direct lactonization of carboxylates
In our second collaborative publication with the Paton group as part of SuPRCat, Katie led a terrific team (Rodrigo, Mihai, Grace, and Sam) to show that base-metal complexes of carboxylic acids can engage in direct …