How do you functionalize a C–C bond? Cade, Caitlin, Matthieu, and Felix have a compelling method for migrating an oxygen atom into an unstrained C(sp3)–C(sp3) bond. In cyclic contexts, this enables the editing of a …
Year: 2025
Direct lactonization of carboxylates
In our second collaborative publication with the Paton group as part of SuPRCat, Katie led a terrific team (Rodrigo, Mihai, Grace, and Sam) to show that base-metal complexes of carboxylic acids can engage in direct …
Temperature control in metallaphotoredox
In a terrific collaborative project with Eli Lilly and the Stahl lab, Caitlin, Max, and Dylan report a method for the synthesis of modified carbohydrates through metallaphotoredox cross-ketonization. Interestingly, this study revealed a profound dependence …